A New Era of Chronic Disease in America and what’s behind it

Richard Lear –  Brown University

August 2017

“There is now increasing evidence that our modern electrical environment is imposing biological stress on our bodies.”

Abstract
A new era of disease is fast emerging in the US. The 21st century model of chronic disease turns the old model upside down. The spotlight has long been on cancer and heart disease, which once were both growing exponentially. Now, among forty fast-growing diseases, the incidence of only three cancers and one cardio-vascular related condition are growing. In their place, four relatively new fast-growing disease groups have emerged: 1) neurological; 2) autoimmune; 3) inflammatory and 4) metabolic disease. A single molecule called peroxynitrite operates at the heart of more than forty fast-growing chronic diseases and conditions in the US. This fast-acting anion creates more than 130 biochemical disruptions in vivo. Among the most troubling is the nitration of L-tryptophan and L-tyrosine, which are precursors to critical neurotransmitters serotonin and dopamine. Peroxynitrite also damages the blood brain barrier (BBB). Such biological markers are hallmarks of neurological diseases like Alzheimer’s, autism, bi-polar disorder and depression.

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